The Harmony Test is a non-invasive prenatal test that analyses the DNA circulating in the pregnant mother’s blood from 10 weeks gestation. It is a new option in prenatal screening for Down syndrome (trisomy 21), Edwards syndrome (trisomy 18 ), Patau’s Syndrome (trisomy 13) and also common chromosomal conditions associated with X and Y chromosome . This test can be requested for any singleton or twin pregnancies, including in vitro fertilization (IVF) pregnancies with egg donors. However, in the twin pregnancies the chromosomal conditions associated with X and Y chromosomes cannot be screened. The Harmony Test is now the most accurate non invasive screening for the most common aneuploidies.