Male reproductive genetic profile


Men with a sperm count less than 10 million/ml may have a problem with their chromosomes so require a Karyotype test to make sure that their Karyotype is 46 XY.

Identifying such problems is important as some problems may have a negative impact on the health of the affected individual and the offspring after successful IVF.

Some of the karyotype problems necessitate Pre-implantation genetic diagnosis (PGD) during the IVF cycle in order to avoid having a baby with congenital defects.

Y chromosome analysis

Men with a sperm count less than 5 million/ml may also have a problem with the AZF genes on the Y chromosome. This test may influence the decision on whether or not to perform surgical sperm retrieval.

Cystic fibrosis screen (CFTR gene tests)

Mutations of the cystic fibrosis gene are involved in male infertility. Some causes of male infertility such as absence of the vas deferens are considered to be mild incomplete forms of cystic fibrosis disease.

It is of utmost importance to also screen the female partner of the affected male for CFTR gene mutations. If the female partner is found to be a carrier of a CFTR gene mutation, Pre-implantation genetic diagnosis (PGD) is necessary to avoid having a child with the full blown picture of cystic fibrosis disease.

IVF Packages With Access Fertility

IVF Packages With Access Fertility
CRGH is partnering with Access Fertility to offer a series of IVF programmes and packages. For more information please click below.

NHS Funding for Fertility Care

CRGH is an NHS approved centre and funding may be available for some patients. You will need to meet certain criteria and be referred to us by your GP. Please call or email us for further information.
Call: +44 (0)20 7837 2905

or click below:

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